How to Properly Suit Up: Cleanroom Smocking Protocols and What Not to Wear

Cleanrooms are essential in industries like semiconductors, pharmaceuticals, biotechnology, and aerospace, where even microscopic contaminants can cause catastrophic failures. That’s why cleanroom entry isn’t just about opening a door; it’s a controlled process of preparation, hygiene, and discipline.

Whether you’re a technician, engineer, or visitor, here’s what you need to know about cleanroom smocking protocols and what not to wear before you enter. 

Step-by-Step Smocking Procedure

  1. Pre-Entry Personal Preparation:
    Before entering the gowning area:

  • Shower if required, or at least wash your hands thoroughly

  • Remove all personal items (jewelry, watches, phones, etc.)

  • Avoid cosmetics and skincare products.

2. Entry into the Gowning Room (Airlock or Ante Room)
Follow a unidirectional flow, from dirty to clean

3. Donning Sequence (Typical Order):
This may vary slightly depending on cleanroom class, but usually includes:

  • Hair cover / bouffant cap

  • Beard cover (if applicable)

  • Face mask - cover nose and mouth properly

  • Shoe covers or cleanroom boots - step over the demarcation line

  • Gloves - Worn over sleeves to ensure wrist seal

  • Coverall or smock - Zipper or snaps must be fully closed

  • Goggles - If required, especially for ISO 4-5 areas. 

  • Second pair of gloves - this is for more stringent classifications

Use a mirror to check that all garments are properly secured and no skin or hair is exposed. 

What You Can’t Wear into a Cleanroom

To maintain the integrity of the cleanroom, the following items and conditions are strictly prohibited:

  1. Personal Accessories:

  • Watches, bracelets, rings, earrings

  • Necklaces or any metal jewelry

  • Harpins or clips that can shed particles

  • Contact lenses in some cases (check site protocol)

2. Cosmetics and Personal Care Products:

  • Perfume or cologne - Fragrances can emit VOCs

  • Hair spray, gel, or wax - These can flake or aerosolize

  • Lotion or makeup - Even powder-free formulations can introduce particulates.

  • Deodorant sticks or sprays - Only approved, residue-free formulations are allowed

3. Clothing Restrictions (under the smock):

  • Lint producing fabrics like wool, fleece, or denim

  • Loose fibers or frayed edges

  • Open-toed shoes or sandals

  • Wear clean, cotton or polyester underclothing that won’t shed lint

Tips for Cleanroom Success

  1. Follow the posted gowning diagram - Each facility has tailored protocols based on ISO classification.

  2. Don’t touch your face or exposed skin once you’ve gloved up.

  3. Move slowly and deliberately - Fast movements stir up particles.

  4. If you touch a contaminated surface or sneeze, exit and regown.

  5. Never bring in pens, notebooks, or tools unless they are cleanroom-approved.



Cleanroom protocols are not just about compliance, it’s about protecting high-value work, sensitive equipment, and human safety. Proper smocking prevents contamination and ensures the controlled environment does what it's designed to do: remain clean. 

Whether you’re new to cleanrooms or training staff, getting smocking right is the first step toward contamination control.

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